TheGrey’s Anatomycast has bid farewell to starJesse Williams.

The actor’sfinal appearanceon the long-running medical drama aired Thursday night, and his costars marked the occasion with some heartfelt tributes to Williams and his character, Dr. Jackson Avery.

Ellen Pompeoposted a selfie with Williams, 39, alongside a caption containing various inspirational quotes.

“‘Life is a balance between holding on & letting go’ — Rumi,” she wrote. “‘Stay far from timid. Only make moves when your heart’s in it. And live the phrase ‘sky’s the limit’ — The Notorious B.I.G. … Thank you @ijessewilliams.”

Kelly McCreary, whose character Maggie Pierce dated Jackson for several seasons, wrote on her own Instagram Story that Williams’ departure marked “the end of an era.”

Kelly McCreary/Instagram

Grey’s Anatomy - JESSE WILLIAMS

Camilla Luddingtonrevealed on her Story that Williams' final scene was opposite her character, Jo Wilson.

“The scene between Jackson and Jo was the last scene @ijessewilliams filmed that episode,” she wrote atop a photo with Williams and fellow costar Kevin McKidd. “Here’s a pic of us all celebrating him right after!”

“And you knowwww it pains me to say this BUT… I’ll really really miss him,” Luddington continued. “I can’t wait to see allll the things he does next.”

Camilla Luddington/Instagram

Grey’s Anatomy - JESSE WILLIAMS

James Pickens Jr.— one of only three actors to have remained onGrey’s for all 17 seasons, alongside Pompeo andChandra Wilson— also posted a tribute to Williams on Instagram.

Williams reposted his costars' kind words on his Instagram Story, adding a special shoutout to Pickens Jr. and Wilson.

“You can’t possibly know how deeply I love these human beings,” he wrote atop a photo of the trio.

Jesse Williams/Instagram

Grey’s Anatomy - JESSE WILLIAMS

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Williams announcedhis departureearlier this month following 12 seasons onGrey’s.

“As an actor, director and person, I have been obscenely lucky to learn so much from so many and I thank our beautiful fans, who breathe so much energy and appreciation into our shared worlds,” continued Williams, who had played the plastic surgeon since season 6.

“The experience and endurance born of creating nearly 300 hours of leading global television is a gift I’ll carry always. I am immensely proud of our work, our impact and to be moving forward with so many tools, opportunities, allies and dear friends.”

Grey’s Anatomyairs Thursdays (9 p.m. ET) on ABC.

source: people.com